We decode the complex dialogue between brain tumors and the immune system using multi-omics and single-cell sequencing to uncover the specific evasion mechanisms and predictive biomarkers that current therapies miss.
Raphael I, et al. Sci Transl Med. 2025
How the extreme conditions of the glioma microenvironment dictate the success or failure of an immune response — and what reprograms it.
Raphael I, et al. Front Immunol. 2021
Rationally combinatorial approaches, from TCR-engineered T cells to vaccines, designed to overcome the immunosuppressive microenvironment for robust tumor elimination.
Xiong Z, et al. Cell Mol Immunol. 2026
JUN 2026
A warm welcome to Dr. Vipin Sharma, joining the lab as a postdoctoral researcher to lead the tumor-immune cross-talk work.
apr 2026
We are thrilled to be selected for the prestigious Zuckerman Faculty STEM Leadership Program to power our research forward.
Mar 2026
Dr. Itay Raphael received the Aryeh Kluger Award for outstanding research in pediatric neuro-oncology as an early-career scientist.
